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      1 /*
      2 Redistribution and use in source and binary forms, with or without
      3 modification, are permitted provided that the following conditions are met:
      4 
      5     * Redistributions of source code must retain the above copyright
      6     notice, this list of conditions and the following disclaimer.
      7 
      8     * Redistributions in binary form must reproduce the above copyright
      9     notice, this list of conditions and the following disclaimer in the
     10     documentation and/or other materials provided with the distribution.
     11 
     12     * Neither the name of "The Computer Language Benchmarks Game" nor the
     13     name of "The Computer Language Shootout Benchmarks" nor the names of
     14     its contributors may be used to endorse or promote products derived
     15     from this software without specific prior written permission.
     16 
     17 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
     18 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
     19 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
     20 ARE DISCLAIMED.  IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE
     21 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
     22 CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
     23 SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
     24 INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
     25 CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
     26 ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
     27 POSSIBILITY OF SUCH DAMAGE.
     28 */
     29 
     30 /*
     31  * http://shootout.alioth.debian.org/u32/program.php?test=fasta&lang=gcc&id=3
     32  */
     33 
     34 /*  The Computer Language Benchmarks Game
     35  *  http://shootout.alioth.debian.org/
     36  *
     37  *  contributed by Petr Prokhorenkov
     38  */
     39 
     40 #include <stdio.h>
     41 #include <stdlib.h>
     42 #include <string.h>
     43 
     44 #ifndef fwrite_unlocked
     45 // not available on OS X
     46 #define fwrite_unlocked fwrite
     47 #define fputc_unlocked fputc
     48 #define fputs_unlocked fputs
     49 #endif
     50 
     51 #define ARRAY_SIZE(a) (sizeof(a)/sizeof(a[0]))
     52 #define unlikely(x) __builtin_expect((x), 0)
     53 
     54 #define IM 139968
     55 #define IA 3877
     56 #define IC 29573
     57 
     58 #define LINE_LEN 60
     59 #define LOOKUP_SIZE 4096
     60 #define LOOKUP_SCALE ((float)(LOOKUP_SIZE - 1))
     61 
     62 typedef unsigned random_t;
     63 
     64 void
     65 random_init(random_t *random) {
     66     *random = 42;
     67 }
     68 
     69 // Special version with result rescaled to LOOKUP_SCALE.
     70 static inline
     71 float
     72 random_next_lookup(random_t *random) {
     73     *random = (*random*IA + IC)%IM;
     74 
     75     return (*random)*(LOOKUP_SCALE/IM);
     76 }
     77 
     78 struct amino_acid {
     79    char sym;
     80    float prob;
     81    float cprob_lookup;
     82 };
     83 
     84 void
     85 repeat(const char *alu, const char *title, int n) {
     86     int len = strlen(alu);
     87     char buffer[len + LINE_LEN];
     88     int pos = 0;
     89 
     90     memcpy(buffer, alu, len);
     91     memcpy(buffer + len, alu, LINE_LEN);
     92 
     93     fputs_unlocked(title, stdout);
     94     while (n > 0) {
     95         int bytes = n > LINE_LEN ? LINE_LEN : n;
     96 
     97         fwrite_unlocked(buffer + pos, bytes, 1, stdout);
     98         pos += bytes;
     99         if (pos > len) {
    100             pos -= len;
    101         }
    102         fputc_unlocked('\n', stdout);
    103         n -= bytes;
    104     }
    105 }
    106 
    107 /*
    108  * Lookup table contains mapping from real values to cumulative
    109  * probabilities. Careful selection of table size allows lookup
    110  * virtually in constant time.
    111  *
    112  * All cumulative probabilities are rescaled to LOOKUP_SCALE,
    113  * this allows to save one multiplication operation on each iteration
    114  * in randomize().
    115  */
    116 
    117 void *
    118 fill_lookup(struct amino_acid **lookup, struct amino_acid *amino_acid, int amino_acid_size) {
    119     float p = 0;
    120     int i, j;
    121 
    122     for (i = 0; i < amino_acid_size; i++) {
    123         p += amino_acid[i].prob;
    124         amino_acid[i].cprob_lookup = p*LOOKUP_SCALE;
    125     }
    126 
    127     // Prevent rounding error.
    128     amino_acid[amino_acid_size - 1].cprob_lookup = LOOKUP_SIZE - 1;
    129 
    130     for (i = 0, j = 0; i < LOOKUP_SIZE; i++) {
    131         while (amino_acid[j].cprob_lookup < i) {
    132             j++;
    133         }
    134         lookup[i] = &amino_acid[j];
    135     }
    136 
    137     return 0;
    138 }
    139 
    140 void
    141 randomize(struct amino_acid *amino_acid, int amino_acid_size,
    142         const char *title, int n, random_t *rand) {
    143     struct amino_acid *lookup[LOOKUP_SIZE];
    144     char line_buffer[LINE_LEN + 1];
    145     int i, j;
    146 
    147     line_buffer[LINE_LEN] = '\n';
    148 
    149     fill_lookup(lookup, amino_acid, amino_acid_size);
    150 
    151     fputs_unlocked(title, stdout);
    152 
    153     for (i = 0, j = 0; i < n; i++, j++) {
    154         if (j == LINE_LEN) {
    155             fwrite_unlocked(line_buffer, LINE_LEN + 1, 1, stdout);
    156             j = 0;
    157         }
    158 
    159         float r = random_next_lookup(rand);
    160         struct amino_acid *u = lookup[(short)r];
    161         while (unlikely(u->cprob_lookup < r)) {
    162             ++u;
    163         }
    164         line_buffer[j] = u->sym;
    165     }
    166     line_buffer[j] = '\n';
    167     fwrite_unlocked(line_buffer, j + 1, 1, stdout);
    168 }
    169 
    170 struct amino_acid amino_acid[] = {
    171    { 'a', 0.27 },
    172    { 'c', 0.12 },
    173    { 'g', 0.12 },
    174    { 't', 0.27 },
    175 
    176    { 'B', 0.02 },
    177    { 'D', 0.02 },
    178    { 'H', 0.02 },
    179    { 'K', 0.02 },
    180    { 'M', 0.02 },
    181    { 'N', 0.02 },
    182    { 'R', 0.02 },
    183    { 'S', 0.02 },
    184    { 'V', 0.02 },
    185    { 'W', 0.02 },
    186    { 'Y', 0.02 },
    187 };
    188 
    189 struct amino_acid homo_sapiens[] = {
    190    { 'a', 0.3029549426680 },
    191    { 'c', 0.1979883004921 },
    192    { 'g', 0.1975473066391 },
    193    { 't', 0.3015094502008 },
    194 };
    195 
    196 static const char alu[] =
    197    "GGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTG"
    198    "GGAGGCCGAGGCGGGCGGATCACCTGAGGTCAGGAGTTCGA"
    199    "GACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAA"
    200    "AATACAAAAATTAGCCGGGCGTGGTGGCGCGCGCCTGTAAT"
    201    "CCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAAC"
    202    "CCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCGCGCCACTG"
    203    "CACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAA";
    204 
    205 int
    206 main(int argc, const char **argv) {
    207     int n = argc > 1 ? atoi( argv[1] ) : 512;
    208     random_t rand;
    209 
    210     random_init(&rand);
    211 
    212     repeat(alu, ">ONE Homo sapiens alu\n", n*2);
    213     randomize(amino_acid, ARRAY_SIZE(amino_acid),
    214             ">TWO IUB ambiguity codes\n", n*3, &rand);
    215     randomize(homo_sapiens, ARRAY_SIZE(homo_sapiens),
    216             ">THREE Homo sapiens frequency\n", n*5, &rand);
    217 
    218     return 0;
    219 }
    220